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July 25, 2020. Mardell Stagner, a lecturer of anatomy at the Museum of the City of New York, discusses the evolution of the nail in 100 million years. The nail is a complex tissue with functions as diverse as protection and sensation; therefore, it has been a reliable model to study the evolution of tissue differentiation. The recognition of the nail’s evolution has led to our current understanding of the molecular mechanisms that guide nail morphogenesis and, ultimately, to more-effective therapeutics for applications ranging from cosmetic dentistry to reconstructive surgery.
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